Genomics and Cancer Epigenetics
Genomics and Cancer Epigenetics focus on understanding the genetic and epigenetic changes that drive cancer development and progression. Genomics refers to the study of an organism's complete set of DNA, including all its genes. In cancer, genomic research seeks to identify mutations, genetic alterations, and abnormal gene expressions that contribute to tumor growth, helping to develop targeted therapies. Cancer epigenetics examines changes in gene expression that are not caused by alterations in the DNA sequence itself, but by other mechanisms such as DNA methylation, histone modification, or non-coding RNA activity. These epigenetic changes can activate oncogenes or silence tumor suppressor genes, contributing to cancer. Understanding both genomic and epigenetic factors is crucial for developing personalized cancer treatments and predicting patient outcomes.
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